Why Mitochondrial Health May Be the Real Foundation of Healthy Aging

Healthy aging is often discussed in terms of hormones, metabolism, exercise, and nutrition, but beneath these factors lies a more fundamental issue: mitochondrial health. Mitochondria are the structures inside our cells that generate energy, regulate oxidative stress, and help coordinate cellular repair. When they function well, the body is better able to maintain resilience, repair […]
Physical Medicine and Rehabilitation

One avenue of regenerative medicine research is an emphasis on developing cell-based therapies to
restore damaged joints. In this Q and A,
Stephen J. Wisniewski, M.D., discusses the status of research
focused on the use of platelet-rich plasma (PRP) and bone marrow aspirate concentrate (BMAC) injections
to treat knee osteoarthritis (OA). Dr. Wisniewski is a physiatrist and sports medicine specialist at Mayo
Clinic in Rochester, Minnesota, whose practice and research focuses include the use of biotherapeutics in
the treatment of arthritis.
NAD+ and Addiction: Understanding Its Role in Brain Function and Recovery

One avenue of regenerative medicine research is an emphasis on developing cell-based therapies to
restore damaged joints. In this Q and A,
Stephen J. Wisniewski, M.D., discusses the status of research
focused on the use of platelet-rich plasma (PRP) and bone marrow aspirate concentrate (BMAC) injections
to treat knee osteoarthritis (OA). Dr. Wisniewski is a physiatrist and sports medicine specialist at Mayo
Clinic in Rochester, Minnesota, whose practice and research focuses include the use of biotherapeutics in
the treatment of arthritis.
Platelet-Rich Plasma

Abstract Purpose: To evaluate the difference in clinical efficacy of platelet-rich plasma (PRP) versushyaluronic acid (HA) in the treatment of knee osteoarthritis (KOA).Methods: This study conducted a comprehensive search of the Cochrane Library, Web of Science,PubMed, CNKI, Wanfang Data, and VIP databases. Eligible studies underwent rigorous quality assessment using the Cochrane Handbook 8.2 Risk of […]
Platelet-Rich Plasma Has Better Results for Long- term

Abstract Background: Corticosteroids (CS) have shown good short-term performance in terms of pain reliefand functional improvement. However, the safety and long-term efficacy of this treatment remainscontroversial. Several studies have reported good results of platelet-rich plasma (PRP) in thetreatment of tendinopathies. However, whether its use in the treatment of lateral epicondylitis (LE)is superior to that of […]
Vitamin D Deficiency and Risk for Cardiovascular Disease

Abstract Vitamin D is an important prohormone for optimal intestinal calcium absorption for mineralization of bone. Because the vitamin D receptor is present in multiple tissues, there has been interest in evaluating other potential functions of vitamin D, particularly, in cardiovascular diseases (CVD). Cross-sectional studies have reported that vitamin D deficiency is associated with increased […]
Effectiveness of platelet-rich plasma in partial- thickness rotator cuff tears: a systematic review

Importance: Partial-thickness rotator cuff tears (PTRCTs) commonly affect overhead athletes, leading to a decline in sports performance. Platelet-rich plasma (PRP) is being explored as an alternative treatment modality for individuals with PTRCTs to reduce discomfort and enhance functional recovery. We conducted a systematic review study of randomized controlled clinical trials to determine the effectiveness of […]
Intravenous Transplantation of Very Small Embryonic Like Stem Cells in Treatment of Diabetes Mellitus

Abstract Background: Diabetes Mellitus (DM), simply known as diabetes, refers to a group of metabolic diseases in which there are high blood sugar levels over a prolonged period. In this study, the feasibility and safety of intravenous transplantation of Very Small Embryonic Like stem cells (VSELs) were investigated for diabetes repair, and finally the migration […]
Changes in NAD+ Levels with Age and Its Impact on Brain Function
THE PENSUM TREATMENT OF HOT FLASHES

Hot flashes are a common symptom experienced by many women during and after menopause but can also occur in men. They are characterized by a sudden warmth or heat that spreads throughout the body, accompanied by sweating and rapid heartbeat.